Acid Reflux Makes Heart Feel Funny

🔥+ Acid Reflux Makes Heart Feel Funny 04 Jun 2020 Gastroesophageal reflux disease or GERD, is a very common disorder and occurs when stomach ... esophagitis, and is useful for those who experience heartburn. ... Breakfast. Apple juice (1/2 cup). Whole-grain cereal (3/4 cup). Banana (1/2).

Acid Reflux Makes Heart Feel Funny Pepto-Bismol is produced by the Procter & Gamble Company and is advertised to relieving heartburn, sour stomach, and acid indigestion.

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Follow all of ScienceDaily'' medical records in a database maintained by the U.S. Department of Veterans Affairs. They identified 275,933 people who had been prescribed a PPI and 73,355 people prescribed an H2 blocker between October 2006 and September 2008, and noted how many died and when over the following five years. The database did not include information on cause of death.

Al-Aly and colleagues found a 25 percent increased risk of death in the PPI group compared with the H2 blocker group. The researchers calculate that, for every 500 people taking PPIs for a year, there is one extra death that would not have otherwise occurred. Given the millions of people who take PPIs regularly, this could translate into thousands of excess deaths every year, Al-Aly said.

The researchers also calculated the risk of death in people who were prescribed PPIs or H2 blockers despite not having the gastrointestinal conditions for which the drugs are recommended. Here, the researchers found that people who took PPIs had a 24 percent increased risk of death compared with people taking H2 blockers.

Further, the risk rose steadily the longer people used the drugs. After 30 days, the risk of death in the PPI and H2 blocker groups was not significantly different, but among people taking the drugs for one to two years, the risk to PPI users was nearly 50 percent higher than that of H2 blocker users.

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Although the recommended treatment regimen for most PPIs is short -- two to eight weeks for ulcers, for example -- many people end up taking the drugs for months or years.

Acid Reflux Makes Heart Feel Funny 7 Natural GERD (⭐️ Nighttime) | Acid Reflux Makes Heart Feel Funny Treatmenthow to Acid Reflux Makes Heart Feel Funny for "" Al-Aly said. ""

As compared with the H2 blocker group, people in the PPI group were older (64 years old, on average, versus 61) and also somewhat sicker, with higher rates of diabetes, hypertension and cardiovascular disease. But these differences cannot fully account for the increased risk of death since the risk remained even when the researchers statistically controlled for age and illness.

Over-the-counter PPIs contain the same chemical compounds as in prescription PPIs, just at lower doses, and there is no way to know how long people stay on them. The Food and Drug Administration recommends taking PPIs no longer than four weeks before consulting a doctor.

Al-Aly emphasizes that deciding whether to take a PPI requires a risk-benefit calculation.

"" Al-Aly said. ""

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Materials provided by Washington University in St. Louis. Original written by Tamara Bhandari. Note: Content may be edited for 1 last update 04 Jun 2020 for style and length.Materials provided by Washington University in St. Louis. Original written by Tamara Bhandari. Note: Content may be edited for style and length.


Journal for 1 last update 04 Jun 2020 Reference:Journal Reference:

  1. Yan Xie, Benjamin Bowe, Tingting Li, Hong Xian, Yan Yan, Ziyad Al-Aly. Risk of death among users of Proton Pump Inhibitors: a longitudinal observational cohort study of United States veterans. BMJ Open, 2017; 7 (6): e015735 DOI: 10.1136/bmjopen-2016-015735

Cite This Page:

Washington University in St. Louis. "" ScienceDaily. ScienceDaily, 5 July 2017. <www.sciencedaily.com/releases/2017/07/170705113546.htm>.
Washington University in St. Louis. (2017, July 5). Popular heartburn drugs linked to higher early death risk. ScienceDaily. Retrieved May 6, 2020 from www.sciencedaily.com/releases/2017/07/170705113546.htm
Washington University in St. Louis. "" ScienceDaily. www.sciencedaily.com/releases/2017/07/170705113546.htm (accessed May 6, 2020).

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